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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194567Generated: October 31, 2026

Trifluoroacetic acid → HCID 178461301, compound

https://huagongshe.com/reaction/2194567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178452028HCID 178452028—
ProductHCID 178461301HCID 178461301—

Reaction Steps

Using the procedure of Example 1 Step 4, (R)-tert-butyl 3-((2-(cis-4-methylcyclohexylamino)-5-(4-morpholinophenyl)pyrimidin-4-yloxy)methyl)pyrrolidine-1-carboxylate was deprotected by TFA to provide the title compound at quantitative yield. MS (ESI) m/z: Found: 452.3 (M+1). Calc. 451.3 (M+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334292B1
Source datasetuspto-grants-2012_12
ORD IDord-d78ae05e230e43abbd78c5abfb11c327
Source noteuspto-grants-2012_12