HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Morpholinopropane-1-sulfonyl chloride → 5-[2-Ethoxy-5-(3-morpholinopropylsulphonamido)phenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Morpholinopropane-1-sulfonyl chloride | HCID 21973189 | — |
| Reactant | 5-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one | HCID 135738560 | — |
| Product | 5-[2-Ethoxy-5-(3-morpholinopropylsulphonamido)phenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one | HCID 135738538 | — |
Reaction Steps
The title compound was prepared from 5-(5-amino-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one and 3-morpholinopropylsulphonyl chloride, following the procedure of Example 41, and was obtained as brown crystals (14%), m.p. 157°-159° C. Found: C,55.42; H,6.53; N,16.01. C24H34N6O5S requires C,55.58; H,6.61; N,16.21%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05426107 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-b7100b06d10e4accb5845d30cfc312c8 |
| Source note | uspto-grants-1995_06 |