Cyclohexanecarboxylic acid → Cyclohexanecarbonyl chloride

HRID 2194627Notes

Reaction equation

HRID 2194627 reaction equation
[CH:1]1([C:7]([OH:9])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:12]>>[CH:1]1([C:7]([Cl:12])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 7413Cyclohexanecarboxylic acidHCID 24386Thionyl Chloride

Product 1

HCID 75938Cyclohexanecarbonyl chloride

Conditions

Temperature
30 °C

Procedure

The mixture of cyclohexylcarboxylic acid (40 g) and SOCl2 (60 mL) was heated at 30° C. for 30 min and then at 50° C. for 3-5 hrs. The volatile materials were removed in vacuum and the residue was used for the next reaction without further purification.

Workup

  1. customThe volatile materials were removed in vacuum
  2. customthe residue was used for the next reaction without further purification

Sources & evidence

ORD record
ord-2dfdb0f3bd504bb690ccf095415b8a56
Source dataset
uspto-grants-2012_12
Patent number
US08334307B2

Reaction notes

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