Potassium Carbonate → HCID 58203528, compound

Participants

Reaction Steps

Acetic acid 2-[6-(3-cyano-5-methyl-benzoyl)-5-isopropyl-3-(4-methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-ethyl ester (88 mg, 0.175 mmol, 1.2 eq.) was dissolved in 1.5 mL MeOH. Potassium carbonate (48 mg, 0.349 mmol, 2 eq.) was added and the reaction mixture was stirred at room temperature for 20 minutes. The reaction mixture was concentrated down and purified (silica gel, 0-10% MeOH/DCM) to give a white powder (76 mg, 94%). LC-MS shows 462.1 (M+1).

Provenance & Evidence