Imidazole → HCID 66761625, compound

HRID 2194860Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6](C)C=[C:4]([Cl:9])[C:3]=1O.[C:11]1(=O)[O:15][CH2:14][CH2:13][O:12]1.N1C=CN=[CH:18]1>>[Cl:9][C:4]1[CH2:3][C:2]([Cl:1])([CH3:18])[CH:7]=[CH:6][C:11]=1[O:12][CH2:13][CH2:14][OH:15]

Participants

Reactant 3

HCID 795Imidazole

HCID 7303Ethylene carbonate

HCID 170772,6-Dichloro-4-methylphenol

Product 1

HCID 66761625HCID 66761625, compound

Conditions

Temperature: 150 °C

Procedure

2,6-Dichloro-4-methylphenol (1 eq.), ethylene carbonate (1 eq.) and imidazole (0.5% loading) were combined and heated at 150° C. for 4 h to afford the title compound as a brown oil.

Sources & evidence

ORD record: ord-d75892c3a5e540bf9eaf522d9547f12e
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08334308B2

Reaction notes

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