HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4-Methyl-3-(trifluoromethyl)bromobenzene | HCID 2775635 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene | HCID 53418031 | — |
Reaction Steps
A solution of commercially available 4-bromo-1-methyl-2-(trifluoromethyl)benzene (1 eq.), NBS (1.1 eq.) and a catalytic amount of benzoyl peroxide in CCl4 (0.21M) was stirred at room temperature for 1 h under a 150 W spot lamp. The mixture was concentrated, purification by column chromatography on silica gel, eluting with Hex, afforded the desired material as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334308B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-1187550e37de4583ae3fcfc85b975dea |
| Source note | uspto-grants-2012_12 |