反应详情

温度

77.5 °C

The Uncoated Dextromethorphan Resin Complex was prepared by first dissolving 95.42 g of dextromethorphan HBr in 0.8 L of purified water heated to 75-80° C., followed by the addition of 175.82 g AMBERLITE IRP-69 resin (anhydrous) under gentle mixing for 4 hours. At the completion, the suspension was allowed to settle, decanted and rinsed with purified water twice and dried in an oven maintained at 50° C. until moisture is around 5%. The dried resin complex was hand sieved through a 40 mesh screen.

1. additionfollowed by the addition of 175.82 g AMBERLITE IRP-69 resin (anhydrous)
2. additionunder gentle mixing for 4 hours
3. customdecanted
4. washrinsed with purified water twice
5. customdried in an oven
6. temperaturemaintained at 50° C. until moisture
7. filtrationsieved through a 40 mesh screen