Hydrogen Peroxide → 1,2-Epoxycyclooctane

The solid mixed phase after extraction in Example 1 was dried under reduced pressure for about 12 hours. 0.110 g (1.00 mmol) of cyclooctene was added to the solid mixed phase after drying under reduced pressure, and stirred well. Further, 0.10 mL (0.90 mmol) of 31% aqueous hydrogen peroxide was added and stirred well. Then, the mixture was allowed to stand still at 25° C. for 24 hours. Thereafter, a colorless solid of epoxycyclooctane was obtained in the same manner as in Example 1. The epoxide yield was 83%.

1. additionThe solid mixed phase
2. extractionafter extraction in Example 1
3. customwas dried under reduced pressure for about 12 hours
4. additionmixed phase
5. customafter drying under reduced pressure
6. stirringstirred well

ORD record

ord-5253119718c3423894984dfe29d12cf8

Source dataset

uspto-grants-2012_12

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US08334394B2