HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 2-amino-5-(2,6-dimethyl-4-morpholinyl)Benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | 5-(2,6-Dimethylmorpholin-4-yl)-2-nitrobenzoic acid | HCID 43176711 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-amino-5-(2,6-dimethyl-4-morpholinyl)Benzoic acid | HCID 54888441 | — |
Reaction Steps
The mixture of 6 g 2-nitro-5-(2,6-dimethylmorpholin-4-yl)benzoic acid, 15 ml cyclohexene and 3 g Pd/C (10%) is heated under reflux for 6 hours. The hot reaction mixture is filtered through a celite pad. After evaporation of the filtrate 4.8 g title product is obtained (MH+: 251).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338411B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-433cddb174df4f15ace534a9d53a86bf |
| Source note | uspto-grants-2012_12 |