Triethylamine → HCID 57876318, compound

HRID 2195886Notes

Reaction equation

HRID 2195886 reaction equation
Br[CH2:2][N:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1.Cl.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17]N)=[CH:13][C:12]=1[F:19].[CH3:20][N:21]1[CH2:26][CH2:25][C:24](=O)[CH2:23][CH2:22]1.[CH2:28](N(CC)CC)C>>[Cl:10][C:11]1[C:12]([F:19])=[CH:13][C:14]2[N:17]([CH2:28][CH2:2][N:3]3[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]3)[C:24]3[CH2:23][CH2:22][N:21]([CH3:20])[CH2:26][C:25]=3[C:15]=2[CH:16]=1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 740491-Methyl-4-piperidoneHCID 19756848HCID 19756848, compoundHCID 53413990(4-Chloro-3-fluorophenyl)hydrazine--hydrogen chloride (1/1)

Product 1

HCID 57876318HCID 57876318, compound

Procedure

The title compound is prepared by following General Method 8 by using 1-(bromomethyl)piperidine, 4-chloro-3-fluorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone.

Sources & evidence

ORD record
ord-f5bb8ceb24c24b559a1ff04f699aa764
Source dataset
uspto-grants-2012_12
Patent number
US08338408B2

Reaction notes

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