HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Formyl-2-thiopheneboronic acid → Di-tert-butyl 1-(5-formylthiophen-2-yl)hydrazine-1,2-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Formyl-2-thiopheneboronic acid | HCID 2773430 | — |
| Reactant | Di-tert-butyl 1-(5-formylthiophen-3-yl)hydrazine-1,2-dicarboxylate | HCID 59843289 | — |
| Product | Di-tert-butyl 1-(5-formylthiophen-2-yl)hydrazine-1,2-dicarboxylate | HCID 59843212 | 47% |
Reaction Steps
Following the same procedure as described for compound 11 (step 1, scheme 2, example 1c) except using 5-formyl-2-thiopheneboronic acid (1.80 g, 11.5 mmol) instead of 5-formylthiophen-3-ylboronic acid to afford 19 (935 mg, 47%) as an orange solid. LRMS (ESI): calc. 342.1; found 343.2 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338437B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b9d796b1d66247bea4b7c739a6a02719 |
| Source note | uspto-grants-2012_12 |