HuagongsheHuagongshe Chemistry Print Report · For research reference only
Di-tert-butyl 1-(5-formylthiophen-2-yl)hydrazine-1,2-dicarboxylate → Di-tert-butyl 1-(5-cyanothiophen-2-yl)hydrazine-1,2-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Di-tert-butyl 1-(5-formylthiophen-2-yl)hydrazine-1,2-dicarboxylate | HCID 59843212 | — |
| Reactant | Di-tert-butyl 1-(5-cyanothiophen-3-yl)hydrazine-1,2-dicarboxylate | HCID 59843278 | — |
| Product | Di-tert-butyl 1-(5-cyanothiophen-2-yl)hydrazine-1,2-dicarboxylate | HCID 59843233 | 75% |
Reaction Steps
Following the same procedure as described for compound 12 (step 2, scheme 2, example 1c) except using 19 (935 mg, 2.73 mmol) instead of 11 to provide compound 20 (692 mg, 75%) as a yellow solid. LRMS (ESI): calc. 339.1; found 340.2 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338437B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-e891dd38a3ce451e965553d98f67a34a |
| Source note | uspto-grants-2012_12 |