HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2197697Generated: October 29, 2026
Hydroxyamine hydrochloride → 6-Propylpyridin-2-amine
https://huagongshe.com/reaction/2197697
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 2-(2,5-Dimethyl-pyrrol-1-yl)-6-propyl-pyridine | HCID 54227779 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Propylpyridin-2-amine | HCID 3016309 | 107.7% |
Reaction Steps
A solution of the product from Example 2b (348 mg, 1.52 mmol) and NH2OH HCl (530 mg, 7.62 mmol) in 4 mL of EtOH/1.5 mL water. Heated at 100° C. for 16 h, cooled to room temperature and extracted with CH2Cl2. Dried over MgSO4 filtered and concentrated under vacuum giving the title compound as an amber oil (223 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08338605B2 |
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| Source dataset | uspto-grants-2012_12 |
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| ORD ID | ord-8f0428fe38ad4c60abf9cc90cf0df5f4 |
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| Source note | uspto-grants-2012_12 |
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