4-Methoxybenzenethiol → 1-(4-Methoxy-phenylsulfanyl)-4-methyl-2-nitro-benzene

HRID 2197770Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5](OS(C(F)(F)F)(=O)=O)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([SH:27])=[CH:23][CH:22]=1>>[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([S:27][C:5]2[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][C:4]=2[N+:16]([O-:18])=[O:17])=[CH:23][CH:22]=1

Participants

Reactant 2

HCID 127654-Methoxybenzenethiol

HCID 713468894-Methyl-2-nitrophenyl trifluoromethanesulfonate

Product 1

HCID 602047921-(4-Methoxy-phenylsulfanyl)-4-methyl-2-nitro-benzeneYield 78%

Procedure

The product from Example 4a (5.0 g, 175 mmol) was reacted with 4-methoxy-benzenethiol (2.45 g, 175 mmol) for 18 h following the procedure from Example 4b giving the product as a solid (3.76 g, 78%).

Sources & evidence

ORD record: ord-69e1bc86581e4080b5c694a29d900a01
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08338605B2

Reaction notes

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