HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 3-(4-Chloro-2-nitro-phenoxy)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 3-(4-Chloro-2-nitro-phenoxy)-benzoyl chloride | HCID 86615500 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(4-Chloro-2-nitro-phenoxy)-benzamide | HCID 68461845 | 92% |
Reaction Steps
The product from Example 168b (1.8 g, 6.13 mmol) was added to cold NH4OH (15 mL) and stirred for 1 h. The reaction was poured into water and extracted with ethyl acetate. The organic layer washed with water, brine, and dried over sodium sulfate, filtered and concentrated under vacuum to gave the title compound (1.66 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-068e560d494046b1aa74b731c8ec7b13 |
| Source note | uspto-grants-2012_12 |