反应详情

The product from Example 168b (1.8 g, 6.13 mmol) was added to cold NH4OH (15 mL) and stirred for 1 h. The reaction was poured into water and extracted with ethyl acetate. The organic layer washed with water, brine, and dried over sodium sulfate, filtered and concentrated under vacuum to gave the title compound (1.66 g, 92%).

1. extractionextracted with ethyl acetate
2. washThe organic layer washed with water, brine
3. dry with materialdried over sodium sulfate
4. filtrationfiltered
5. concentrationconcentrated under vacuum