HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitro-4-trifluoromethyl-biphenyl → 4-(Trifluoromethyl)[1,1′-biphenyl]-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitro-4-trifluoromethyl-biphenyl | HCID 11300119 | — |
| Reactant | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(Trifluoromethyl)[1,1′-biphenyl]-2-amine | HCID 11736526 | — |
Reaction Steps
The product from Example 218a was reacted as described in Example 212c substituting 3:1 THF/EtOH (4 mL) for ethanol to give the title amine in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-ea0ef3ede4a747fda7af98af3784dd82 |
| Source note | uspto-grants-2012_12 |