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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198024Generated: October 31, 2026

4-Bromo-2-chloro-alpha,alpha,alpha-trifluorotoluene → HCID 67022225, compound

https://huagongshe.com/reaction/2198024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-chloro-alpha,alpha,alpha-trifluorotolueneHCID 67959—
ReactantEthyl 3-(pyrrolidin-3-yl)propanoateHCID 53428732—
ProductHCID 67022225HCID 6702222561%

Reaction Steps

The title compound (5.0 g, yield 61%) was obtained from 4-bromo-1-chloro-2-(trifluoromethyl)benzene and ethyl 3-(pyrrolidin-3-yl)propanoate obtained in Reference Example 12 by a method similar to that in Reference Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338622B2
Source datasetuspto-grants-2012_12
ORD IDord-0216687dcc0048598625a2ece54bc722
Source noteuspto-grants-2012_12