HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67022229, compound → HCID 87239791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67022229 | HCID 67022229 | — |
| Reactant | HCID 67022294 | HCID 67022294 | — |
| Reactant | HCID 87239830 | HCID 87239830 | — |
| Product | HCID 87239791 | HCID 87239791 | — |
Reaction Steps
A mixture of 1-[2-chloro-3-(trifluoromethyl)phenyl]pyrrolidin 3-yl 4-methylbenzenesulfonate and 1-[3-(trifluoromethyl)phenyl]pyrrolidin-3-yl 4-methylbenzenesulfonate was obtained as white crystals (3.35 g, yield 69%) from a mixture of 1-[2-chloro-3-(trifluoromethyl)phenyl]pyrrolidin-3-ol and 1-[3-(trifluoromethyl)phenyl]pyrrolidin-3-ol obtained in Reference Example 26 by a method similar to that in Reference Example 24. This was used for the next reaction without performing further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338622B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-214a2810429a44248d17e5878927a2b6 |
| Source note | uspto-grants-2012_12 |