Dimethylamine → HCID 68743533, compound

HRID 2198260Notes

Reaction equation

HRID 2198260 reaction equation
[C:1]([NH:8][C:9]1[S:10][C:11]2[CH2:22][CH2:21][CH2:20][CH2:19][C:12]=2[C:13]=1[C:14](OCC)=[O:15])(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH3:23][NH:24][CH3:25]>>[C:1]([NH:8][C:9]1[S:10][C:11]2[CH2:22][CH2:21][CH2:20][CH2:19][C:12]=2[C:13]=1[C:14]([N:24]([CH3:25])[CH3:23])=[O:15])(=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 1752437HCID 1752437, compound

Product 1

HCID 68743533HCID 68743533, compound

Procedure

The product of Example 33 and dimethylamine were processed as in Examples 29A and 29B to afford the title compound. 1H NMR (300 MHz, CDCl3) δ ppm 0.88-0.96 (m, 4H), 1.29-1.41 (m, 4H), 1.54-1.72 (m, 3H), 1.73-1.91 (m, 3H), 2.33-2.42 (m, 4H), 2.63-2.71 (m, 2H), 2.92 (s, 3H), 3.05 (s, 3H); MS (DCI/NH3) m/z 323 (M+H)+; anal. calculated for C17H26N2O2S.0.75C8H17NO.0.3H2O: C, 63.46; H, 9.11; N, 8.85. Found: C, 63.15; H, 9.46; N, 8.66.

Sources & evidence

ORD record
ord-010ea9e9ee624ccbac2360fa1e3e23e1
Source dataset
uspto-grants-2012_12
Patent number
US08338623B2

Reaction notes

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