Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198490Generated: October 31, 2026

Thionyl Chloride → HCID 20520138, compound

https://huagongshe.com/reaction/2198490

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant2-Amino-4-chlorobenzoic acidHCID 66646—
Reactant4-Chloro-8-(trifluoromethyl)quinolineHCID 90262—
ReactantHCID 20520129HCID 20520129—
ReactantHCID 20520134HCID 20520134—
ProductHCID 20520138HCID 20520138—

Reaction Steps

4-Chloromethyl-2-(8-trifluoromethyl-4-quinolylamino)benzoyl chloride hydrochloride prepared by reaction of 4-chloro-8-trifluoromethylquinoline with 2-amino-4-chlorobenzoic acid and treatment of the reaction product with thionyl chloride, is reacted with 3-amino-1-butylpiperidine to form the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04357333
Source datasetuspto-grants-1982_11
ORD IDord-7b2870ad3dcb4bb6b21827ef7af6684e
Source noteuspto-grants-1982_11