HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → N-(4-Dipropylaminobutyl)-3-methyl-N-propyl-2-(8-trifluoromethyl-4-quinolylamino)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Amino-3-methylbenzoic acid | HCID 78101 | — |
| Reactant | 4-Chloro-8-(trifluoromethyl)quinoline | HCID 90262 | — |
| Reactant | 3-Methyl-2-(8-trifluoromethyl-4-quinolylamino)benzoyl chloride hydrochloride | HCID 20520130 | — |
| Reactant | 1-Dipropylamino-4-propylaminobutane | HCID 20520150 | — |
| Product | N-(4-Dipropylaminobutyl)-3-methyl-N-propyl-2-(8-trifluoromethyl-4-quinolylamino)benzamide | HCID 20520120 | — |
Reaction Steps
3-Methyl-2-(8-trifluoromethyl-4-quinolylamino)benzoyl chloride hydrochloride prepared by the reaction of 4-chloro-8-trifluoromethylquinoline with 2-amino-3-methylbenzoic acid and treatment of the reaction product with thionyl chloride, is reacted with 1-dipropylamino-4-propylaminobutane to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04357333 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-0f1a37954e8e4436a0cc07408d0619cc |
| Source note | uspto-grants-1982_11 |