(Z)-2-(2-Tritylaminothiazol-4-yl)-2-methoxyiminoacetic acid → HCID 53835278, compound

Participants

Reaction Steps

O-mesitylenesulfonylhydroxylamine (1.3 g.) was added at room temperature to a stirred suspension of 2-(2-tritylamino-4-thiazolyl)-2-methoxyimino acetic acid (2.15 g) in methylene chloride (40 ml), thus giving in a few minutes the complete dissolution of the reaction mixture. Stirring was maintained for 18 hours, during which time the mesitylenesulfonic salt of the title compound slowly separates as a white solid. The product was filtered and washed with ethyl ether, thus giving 2.98 g (92%) of 2-(2-tritylimino-3-amino-4-thiazolinyl)-2-methoxyimino acetic acid, mesitylene sulfonate, m.p.=161°-163° dec.

Provenance & Evidence