Sodium Chloride → 2,5,6,6-Tetramethylcyclohex-1-ene-1-carbaldehyde

Participants

Reaction Steps

16.6 g of 5-methyl-α-cyclocitral were added dropwise, at 0°-5° C., to a solution of 6.4 g of KOH in 110 ml of methanol, after which the reaction mixture was kept for 80 minutes at 0°-5° C. It was then poured onto 250 ml of ice water and the mixture was saturated with sodium chloride and extracted 5 times with 50 ml of ether at a time. The combined extracts were washed twice with 50 ml of saturated sodium chloride solution at a time, and were dried with anhydrous sodium sulfate.

Provenance & Evidence