Salicyl Alcohol → 2-[(Ethylsulfanyl)methyl]phenol

HRID 2198590Notes

Reaction equation

HRID 2198590 reaction equation
O[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[OH:9].[CH2:10]([SH:12])[CH3:11]>>[CH2:10]([S:12][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[OH:9])[CH3:11]

Participants

3

Reactant 2

HCID 5146Salicyl AlcoholHCID 6343Ethanethiol

Product 1

HCID 5221672-[(Ethylsulfanyl)methyl]phenolYield 96%

Procedure

A mixture of 49.6 g (0.4 mol) of 2-hydroxymethyl-phenol and 124 g (2 mol) of ethylmercaptan was heated for 5 hours to 170° C. in a stirred autoclave. Working up as in Example 1 gave 32.2 g (96% of theory) of 2-ethylthiomethyl-phenol.

Workup

  1. temperaturewas heated for 5 hours to 170° C. in a stirred autoclave

Sources & evidence

ORD record
ord-eacb17e009e84059b307f1326fc1641a
Source dataset
uspto-grants-1982_11
Patent number
US04358616

Reaction notes

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