Salicyl Alcohol → 2-[(Ethylsulfanyl)methyl]phenol

HRID 2198594Notes

Reaction equation

HRID 2198594 reaction equation
O[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[OH:9].[CH2:10]([SH:12])[CH3:11]>>[CH2:10]([S:12][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[OH:9])[CH3:11]

Participants

3

Reactant 2

HCID 5146Salicyl AlcoholHCID 6343Ethanethiol

Product 1

HCID 5221672-[(Ethylsulfanyl)methyl]phenol

Procedure

49.6 g (0.4 mol) of 2-hydroxymethyl-phenol were reacted with 24.8 g (0.4 mol) of ethylmercaptan in 200 ml of solvent or diluent for 5 hours at 170° C. under autogenous pressure in a VA stirred autoclave. Depending on the solvent or diluent, working up by distillation gave the following yields of 2-ethylthiomethyl-phenol (Table 1):

Workup

  1. distillationdiluent, working up by distillation
  2. customgave the

Sources & evidence

ORD record
ord-8198ea50695c4b82826cdebbff718b81
Source dataset
uspto-grants-1982_11
Patent number
US04358616

Reaction notes

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