Water → Tetrabutylammonium Hydroxide

HRID 2198775Notes

Reaction equation

HRID 2198775 reaction equation
[CH2:1]([N+:5]([CH2:14][CH2:15][CH2:16][CH3:17])([CH2:10][CH2:11][CH2:12][CH3:13])[CH2:6][CH2:7][CH2:8][CH3:9])[CH2:2][CH2:3][CH3:4].[OH2:18]>C(Cl)(Cl)Cl>[OH-:18].[CH2:14]([N+:5]([CH2:1][CH2:2][CH2:3][CH3:4])([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:10][CH2:11][CH2:12][CH3:13])[CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 962WaterHCID 16028Tetrabutylammonium

Product 1

HCID 2723671Tetrabutylammonium Hydroxide

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The corresponding salts of formula (V) or (VI) where M is tetrabutylammonium can be obtained from the corresponding acid, e.g. by neutralization with aqueous tetrabutylammonium hydroxide in the presence of a water immiscible organic solvent, preferably chloroform. The solvent layer is separated and the product isolated by evaporation of solvent. Alternately, the sodium or potassium salts of formula (V) or (VI) are reacted with an equimolar amount of aqueous tetrabutylammonium hydrogen sulfate in the presence of a water immiscible solvent, the precipitated alkali metal bisulfate salt removed by filtration and the product isolated by evaporation of solvent.

Sources & evidence

ORD record
ord-bfe757df43024460a429cff811b0296c
Source dataset
uspto-grants-1982_11
Patent number
US04359472

Reaction notes

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