O-Cresol → 2,6-Dimethylphenol

HRID 2198799Notes

Reaction equation

HRID 2198799 reaction equation
[C:1]1([CH3:8])[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9]O.[O-2].[Ca+2]>[O-2].[Fe+2].[O-2].[Ti+4].[O-2].[O-2].[Cr+3].[O-2].[O-2].[Cr+3].O>[C:6]1([OH:7])[C:5]([CH3:9])=[CH:4][CH:3]=[CH:2][C:1]=1[CH3:8]

Participants

8

Reactant 3

HCID 335O-CresolHCID 887MethanolHCID 6850728Calciumoxide

Product 1

HCID 113352,6-Dimethylphenol

Reagents, catalysts & solvents 4

HCID 162651Titanium oxide (Ti3O)CatalystHCID 165971Chromium oxideCatalystHCID 449809Ferrous oxideCatalystHCID 962WaterSolvent

Procedure

o-cresol, methanol and water in a ratio of 1:2.5:2.5 were reacted in the same way as in Example 1. The catalyst contained iron oxide, titanium oxide, chromium oxide and calcium oxide in a molar ratio of 100:4,5:2:0,5. After working up, 2,6-xylenol was obtained with a selectivity of 99.1%.

Sources & evidence

ORD record
ord-15c09a54d2284b18b72f9dddf527cbc6
Source dataset
uspto-grants-1982_11
Patent number
US04359591

Reaction notes

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