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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198841Generated: October 26, 2026

M-Cresol → Toliprolol

https://huagongshe.com/reaction/2198841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
Reactant1-(Propan-2-yl)azetidin-3-olHCID 544677—
ProductToliprololHCID 1804781%

Reaction Steps

1-(iso-propyl)-3-azetidinol and m-cresol were reacted in the same manner as in Example 6 to yield 1-(3'-methylphenoxy)-3-(iso-propylamino)-2-propanol melting at 80°-82° C. The yield was 81%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04360464
Source datasetuspto-grants-1982_11
ORD IDord-2b89608db35f4d60951f14fb8074c153
Source noteuspto-grants-1982_11