Thionyl Chloride → 1-(Chloromethyl)-2-iodobenzene

HRID 2198863Notes

Reaction equation

HRID 2198863 reaction equation
[I:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4]O.S(Cl)([Cl:12])=O>>[I:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][Cl:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 1076292-Iodobenzylic alcohol

Product 1

HCID 1010641-(Chloromethyl)-2-iodobenzene

Procedure

o-Iodobenzyl chloride was prepared from o-iodobenzyl alcohol using thionyl chloride according to the procedure described by Brooks et al, Org. Syn. Coll. Vol. 3, p. 698 (1955). The crude product was distilled at reduced pressure to yield a clear, colorless liquid having a bp of 143°/4 mm Hg.

Workup

  1. distillationThe crude product was distilled at reduced pressure
  2. customto yield a clear, colorless liquid

Sources & evidence

ORD record
ord-f48a423008164f6f8117619f5f364853
Source dataset
uspto-grants-1982_11
Patent number
US04360511

Reaction notes

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