HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 20517518, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethylene Oxide | HCID 6354 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| Reactant | 3-Methoxy-1-phenylbutan-1-one | HCID 13065940 | — |
| Product | HCID 20517518 | HCID 20517518 | — |
Reaction Steps
Following the method of Example 1,2-(3-methoxyphenyl)-2-propyloxiran was prepared from trimethylsulphoxonium iodide, 3-methoxybutyrophenone and sodium hydride. The oxiran was treated with 33% ethanolic methylamine affording 3-methoxy-α-[(methylamino)methyl]-α-propylbenzenemethanol isolated as the hydrochloride salt m.p. 168°-70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04360519 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-2bf52759f51a40aa8637394bfe7fb81c |
| Source note | uspto-grants-1982_11 |