反应详情

A mixture of 390 mg. (1.02 mmols.) of 4-[2-benzyloxy-4-(1,1-dimethylheptyl)phenyl]-2-butanol, 360 mg. of solid sodium bicarbonate, 100 mg. of 10% palladium-on-carbon and 10 ml. of ethanol was stirred under one atmosphere of hydrogen for 20 minutes. The reaction mixture was filtered through diatomaceous earth with ethyl acetate and evaporated to an oil. The oil was purified via rapid column chromatography on silica gel eluted with ether to give a quantitative yield of the title compound as an oil.

1. additionA mixture of 390 mg
2. filtrationThe reaction mixture was filtered through diatomaceous earth with ethyl acetate
3. customevaporated to an oil
4. customThe oil was purified via rapid column chromatography on silica gel
5. washeluted with ether