Hydrochloric Acid → HCID 178448086, compound

Participants

Reaction Steps

Trans-4-n-propylcyclohexane carboxylic acid (23.8 g, 0.14 mole), was dissolved in 150 ml of dry ether and added dropwise with stirring into a suspension of 11.4 g (0.3 mole) of LiAlH4 in 300 ml of ether. After the addition the mixture was heated for 2 hours at reflux, and then the supernatant LiAlH4 was decomposed with water while being cooled. The reaction mixture was then poured onto 20% hydrochloric acid and stirred until the inorganic salts dissolved. The product of formula (31) was extracted with diethyl ether; the combined organic phases were washed with water, dried with MgSO4 and concentrated.

Provenance & Evidence