HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholino(4-nitro-3-(trifluoromethyl)phenyl)methanone → (4-Amino-3-(trifluoromethyl)phenyl)(morpholino)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholino(4-nitro-3-(trifluoromethyl)phenyl)methanone | HCID 68936908 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Amino-3-(trifluoromethyl)phenyl)(morpholino)methanone | HCID 62155530 | — |
Reaction Steps
A mixture of EXAMPLE 144A (13 g) and Pd/C (1.3 g, 10%) in ethanol (300 mL) was stirred under hydrogen at room temperature for two days. The catalyst was filtered off and the solvent was evaporated to provide the final compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359296B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-607605d4353444b1a8ece2c5695ccfdf |
| Source note | uspto-grants-2016_06 |