Methane → HCID 22854044, compound

HRID 21999Notes

Reaction equation

HRID 21999 reaction equation
[OH:1][C:2]1([C:27]#[C:28][C:29]([OH:31])=[O:30])[CH2:7][CH2:6][C@:5]2([OH:26])[C@H:8]3[C@H:18]([CH2:19][CH2:20][C@:3]12[CH3:4])[C@:16]1([CH3:17])[C@@H:11]([CH2:12][C@@H:13]([O:21][CH2:22][O:23][CH2:24][CH3:25])[CH2:14][CH2:15]1)[CH2:10][CH2:9]3.C>C(O)C.[Pd]>[OH:1][C:2]1([CH2:27][CH2:28][C:29]([OH:31])=[O:30])[CH2:7][CH2:6][C@:5]2([OH:26])[C@H:8]3[C@H:18]([CH2:19][CH2:20][C@:3]12[CH3:4])[C@:16]1([CH3:17])[C@@H:11]([CH2:12][C@@H:13]([O:21][CH2:22][O:23][CH2:24][CH3:25])[CH2:14][CH2:15]1)[CH2:10][CH2:9]3

Participants

5

Reactant 2

HCID 297MethaneHCID 22854046HCID 22854046, compound

Product 1

HCID 22854044HCID 22854044, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 17-hydroxy-17-carboxyethynyl-3beta-ethoxymethoxy-14-hydroxy-5beta,14beta-androstane (30 mg), prepared as described in Example 12, in ethanol (5 ml), was hydrogenated at 2.72 atmosphere in a Parr apparatus in the presence of 10% palladium over charcoal.

Sources & evidence

ORD record
ord-dedaec85bf7843bc866a0ca2b2d1f275
Source dataset
uspto-grants-1995_06
Patent number
US05426179

Reaction notes

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