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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2199936Generated: October 30, 2026

3-(Trifluoromethyl)benzyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/2199936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzyl chlorideHCID 69716—
Reactant2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
ProductHCID 68184353HCID 68184353—

Reaction Steps

The titled compound (38 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 3-(trifluoromethyl)benzyl chloride according to the method of the process (7) of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359350B2
Source datasetuspto-grants-2016_06
ORD IDord-e7d377cbd5604ccbadc77e17ef73bd0e
Source noteuspto-grants-2016_06