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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2199979Generated: October 30, 2026

Isoxazole, 4-(chloromethyl)-3,5-dimethyl- → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/2199979

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoxazole, 4-(chloromethyl)-3,5-dimethyl-HCID 88246—
ReactantHCID 60152152HCID 60152152—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
ProductHCID 68184445HCID 68184445—

Reaction Steps

The titled compound (16.5 mg) as a white solid was prepared from the compound [102-4] obtained in the process (4) of Example 102 (21.0 mg) and 4-(chloromethyl)-3,5-dimethylisoxazole according to the method of the process (5) of Example 102.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359350B2
Source datasetuspto-grants-2016_06
ORD IDord-09afe95dede6482aa210a8ec3ec11451
Source noteuspto-grants-2016_06