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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2199982Generated: October 30, 2026

2,4,6-Trimethylbenzyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/2199982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzyl chlorideHCID 74108—
ReactantHCID 60152152HCID 60152152—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
ProductHCID 68184447HCID 68184447—

Reaction Steps

The titled compound (10.3 mg) as a white solid was prepared from the compound [102-4] obtained in the process (4) of Example 102 (21.2 mg) and 2,4,6-trimethylbenzyl chloride according to the method of the process (5) of Example 102.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359350B2
Source datasetuspto-grants-2016_06
ORD IDord-a7f3f0121ce14779b471f1e54f109225
Source noteuspto-grants-2016_06