HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-ethoxy-N'-hydroxypropanimidamide → {3-[3-(2-Ethoxyethyl)-1,2,4-oxadiazol-5-yl]-5-(4-ethylphenyl)piperidin-1-yl}(thiomorpholin-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-ethoxy-N'-hydroxypropanimidamide | HCID 5044387 | — |
| Reactant | 5-(4-Ethylphenyl)-1-(thiomorpholin-4-ylcarbonyl)piperidine-3-carboxylic acid | HCID 58116464 | — |
| Product | {3-[3-(2-Ethoxyethyl)-1,2,4-oxadiazol-5-yl]-5-(4-ethylphenyl)piperidin-1-yl}(thiomorpholin-4-yl)methanone | HCID 59606585 | — |
Reaction Steps
According to General Method 6A, 600 mg (1.655 mmol) of the compound from Example 7A and 355 mg (approx. 2.152 mmol) of 3-Ethoxy-N′-hydroxypropanimidamide were reacted Yield: 389 mg (49% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202862B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-db1206c9c08d4cf8822433fd66e7d0e3 |
| Source note | uspto-grants-2012_06 |