Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 15284091 | HCID 15284091 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 15284092 | HCID 15284092 | — |
Reaction Steps
A mixture of 6-Carboethoxy-2,4-dichloro-5,6,7,8-tetrahydroquinazoline (7.68 g), 2-propanol (7 mL) and 30% ammonium hydroxide (12 mL) was heated in a sealed tube at 130° C. for 20 min. The tube was cooled and 20 mL of H2O was added to the mixture. The solid which precipitated was collected and dried to yield 4-Amino-6-carboethoxy-2-chloro-5,6,7,8-tetrahydroquinazoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05426186 |
|---|
| Source dataset | uspto-grants-1995_06 |
|---|
| ORD ID | ord-9b0014b90875450599bb8794904fd624 |
|---|
| Source note | uspto-grants-1995_06 |
|---|
