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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2200595Generated: October 30, 2026

HCID 90440991, compound → HCID 90403348, compound

https://huagongshe.com/reaction/2200595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90440991HCID 90440991—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 90403348HCID 9040334899.4%

Reaction Steps

To a solution of (E)-ethyl 3-(5-methylthiazol-2-yl)acrylate (200 mg, 1.01 mmol,) in methanol (5 mL) was added 5% Pd/C (20 mg). The reaction was purged with nitrogen and then hydrogen and then was stirred under a hydrogen atmosphere (balloon). The reaction was filtered. The filtrate was concentrated to give ethyl 3-(5-methylthiazol-2-yl)propanoate (200 mg, 99% yield) as a light yellow oil. LCMS retention time 1.33 min; LCMS MH+ 200.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359359B2
Source datasetuspto-grants-2016_06
ORD IDord-a5163f2461d94ddd90b36bb88ec614c4
Source noteuspto-grants-2016_06