反应详情

In DCM (20 mL) was dissolved N-benzyl-4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-formamide (201 mg, 0.47 mmol). Then was added m-CPBA (80 mg, 0.47 mmol). The reaction was conducted at ambient temperature for 5 h. After the reaction was completed, the reaction mixture was washed with water and extracted with DCM. The organic phase was dried, and the solvent was removed by rotary evaporation. The obtained solid was used in the subsequent procedure without further purification.

1. washthe reaction mixture was washed with water
2. extractionextracted with DCM
3. customThe organic phase was dried
4. customthe solvent was removed by rotary evaporation
5. customThe obtained solid was used in the subsequent procedure without further purification