HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Aminocyclopentane-1-carboxamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Tert-butoxycarbonylamino-1-cyclopentanecarboxamide | HCID 10680867 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-Aminocyclopentane-1-carboxamide hydrochloride | HCID 54593188 | — |
Reaction Steps
A solution of tert-butyl 1-carbamoylcyclopentylcarbamate (305 mg, 1.33 mmol) in 4N HCl in dioxane (5 mL) and aq. 6N HCl (3 mL) was stirred at room temperature for 3 h. It was then concentrated in vacuo to give 1-aminocyclopentanecarboxamide hydrochloride as a solid (214 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359375B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-4036f8f0fed94f1b833b2e6ce1196f41 |
| Source note | uspto-grants-2016_06 |