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HRID220139

反应详情

EQUATION

反应方程式

HRID 220139 的结构方程式

REACTANTS

反应物

2
结构：[NH4+].[OH-]
HCID14923

Ammonium hydroxide

H5NO

结构：CCOC(=O)C[C@H]1CC[C@H](c2ccc(C(=O)Cl)cc2)CC1
HCID178471771

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C[C@H]1CC[C@H](c2ccc(C(N)=O)cc2)CC1
HCID178471768

未命名化合物

收率 100%

PROCEDURE

实验过程

Ammonium hydroxide (large excess) was added to the product from Example 1C (8.43 g, 27.3 mmol) at room temperature. White solids precipitated out and were collected by filtration and washed with water to afford the title compound (7.9 g, 100%) as a white solid which was taken on to the next step without further purification. MS (DCI) m/z 290.1 [M+H]+.

WORKUP

后处理

  1. customWhite solids precipitated out
  2. filtrationwere collected by filtration
  3. washwashed with water