Sodium Nitrite → HCID 178526298, compound

HRID 2201471Notes

Reaction equation

HRID 2201471 reaction equation
N([O-])=[O:2].[Na+].N[C:6]1[N:7]=[N+:8]([O-:17])[C:9]2[CH:15]=[C:14]([OH:16])[CH:13]=[CH:12][C:10]=2[N:11]=1>C(O)(C(F)(F)F)=O>[OH:2][C:6]1[N:7]=[N+:8]([O-:17])[C:9]2[CH:15]=[C:14]([OH:16])[CH:13]=[CH:12][C:10]=2[N:11]=1

Participants

4

Reactant 2

HCID 23668193Sodium NitriteHCID 178508192HCID 178508192, compound

Product 1

HCID 178526298HCID 178526298, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Conditions

Temperature
20 °C

Procedure

Sodium nitrite (22 mmol) was added in small portions to a stirred solution of 3-amino-7-hydroxybenzo[e][1,2,4]triazine 1-oxide (20 mmol) in TFA (40 mL) at 5° C., and the solution stirred at 20° C. for 3 h. The solution was poured into ice/water (400 mL), stirred 30 min, filtered, washed with water (3×10 mL) and dried.

Workup

  1. stirringstirred 30 min
  2. filtrationfiltered
  3. washwashed with water (3×10 mL)
  4. customdried

Sources & evidence

ORD record
ord-9e7dbe1b9c08470a9ec0559c472d2af6
Source dataset
uspto-grants-2016_06
Patent number
US09364481B2

Reaction notes

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