Thionyl Chloride → 2,6-Dichloro-4-(methylcarbamoyl)benzoyl chloride

Participants

Reaction Conditions

Reaction Steps

A mixture of 2,6-dichloro-4-(methylcarbamoyl)benzoic acid (400 mg, 1.6 mmol) and thionyl chloride (1.91 g, 16 mmol) in dichloromethane (10 mL) was stirred at 50° C. for 5 hours. The reaction mixture was concentrated under rotary evaporator and used as such for next step.

Provenance & Evidence