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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2201924Generated: October 30, 2026

Hydrochloric Acid → HCID 78320096, compound

https://huagongshe.com/reaction/2201924

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 118558219HCID 118558219—
ProductHCID 78320096HCID 78320096—

Reaction Steps

To (R)-tert-butyl 2-methyl-2-(3-(4′-(2-(2-methylpyrrolidin-1-yl)ethyl)biphenyl-4-yl)propanamido)propanoate 2,2,2-trifluoroacetate (2.0 mg, 3.37 mol) was added 4M hydrogen chloride in dioxane (0.295 mL, 1.181 mmol). The reaction was stirred at room temperature for 4 h. The mixture was concentrated to give the title compound. LCMS m/z=423.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365511B2
Source datasetuspto-grants-2016_06
ORD IDord-da08c2e2189d400dbdf5f623dc428182
Source noteuspto-grants-2016_06