Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2201936Generated: October 30, 2026

Hydrochloric Acid → HCID 78320717, compound

https://huagongshe.com/reaction/2201936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 118558228HCID 118558228—
SolventMethanolHCID 887—
ProductHCID 78320717HCID 78320717—

Reaction Steps

To a solution of (R)-methyl 2-(3-(4′-(2-(2-methylpyrrolidin-1-yl)ethyl)biphenyl-4-yl)propanamido)acetate 2,2,2-trifluoroacetate (18 mg, 0.034 mmol) in MeOH (0.5 mL) was added 5M sodium hydroxide (0.048 mL, 0.241 mmol). The reaction was stirred at room temperature overnight. The mixture was added 1M HCl (2 mL) and purified by HPLC to give the title compound. LCMS m/z=395.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365511B2
Source datasetuspto-grants-2016_06
ORD IDord-5f9060a533a54af28637a5310138ec69
Source noteuspto-grants-2016_06