Hydrochloric Acid → HCID 78320718, compound

Participants

Reaction Steps

To (1R,2R)-ethyl 2-(1-(4′-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)biphenyl-4-yl)cyclopentanecarboxamido)cyclohexanecarboxylate 2,2,2-trifluoroacetate (2.7 mg, 4.19 μmol) was added 5M sodium hydroxide (0.017 mL, 0.084 mmol). The reaction was stirred at room temperature overnight. The mixture was neutralized with 4M HCl in dioxane. The mixture was concentrated and triturated with acetonitrile to give the title compound. LCMS m/z=503.5 [M+H]+.

Provenance & Evidence