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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2201940Generated: October 29, 2026

Hydrochloric Acid → HCID 78321034, compound

https://huagongshe.com/reaction/2201940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 118558217HCID 118558217—
ProductHCID 78321034HCID 78321034—

Reaction Steps

To (R)-tert-butyl 4-(1-(4′-(2-(2-methylpyrrolidin-1-yl)ethyl)biphenyl-4-yl)cyclopentanecarboxamido)butanoate 2,2,2-trifluoroacetate (2.6 mg, 4.11 μmol) was added 4M hydrogen chloride in dioxane (0.103 mL, 0.411 mmol). The reaction was stirred at room temperature overnight. The mixture was concentrated to give the title compound. LCMS m/z=463.4 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365511B2
Source datasetuspto-grants-2016_06
ORD IDord-68001557dea84ac7b7bbd407e04a6f78
Source noteuspto-grants-2016_06